Development of the insecticide oxazosulfyl

抄録

Oxazosulfyl, a novel insecticide originally discovered and developed by Sumitomo Chemical Co., Ltd., belongs to a new chemical class, the sulfyl group, structurally characterized by its ethylsulfonyl moiety. It exhibits excellent control against a broad range of major rice insect pests, including Coleoptera, Hemiptera, Lepidoptera, and Orthoptera, through nursery-box application. With a novel structural backbone and mode of action, this insecticide is classified by the Insecticide Resistance Action Committee as the sole member of novel code 37, vesicular acetylcholine transporter inhibitor. A substantial number of field studies in rice paddy fields have demonstrated that oxazosulfyl, registered in Japan in April 2021 as ALLES^® granules, is highly effective against populations that have developed reduced sensitivity or resistance to existing insecticides. Given these favorable properties, oxazosulfyl is expected to contribute to the management of insecticide resistance, the reduction of agricultural chemical use, labor savings, and sustainable agriculture as a next-generation insecticide.