酵母の銅に対する適応的変異現象の研究 XII.

銅耐性変異株の耐性機序としてのアミノ酸合成能

抄録

1. The effect of various amino acids alleviating the copper injury of a strain of S. ellipsoideus was observed with three methods; a) determination of the highest copper concentration which does not permit a preferential growth of secondary resistant colonies on the streaked parent strain; b) comparison of the survival ratios of the parent strain and of a copper-trained substrain at various copper concentrations; c) reversal of copper inhibition of CO2 evolution.
2. The inhibition by copper was much reduced by the presence of Na-glutamate or Na-aspartate in the medium.
3. The copper resistance of the predominating resistant strain, R^1b, seems to rest on the ability of synthesizing gultamic acid in the presence of copper.