遊走腎の研究
腎血流障害時のRPFとLDH及びその Isozyme の変動について―実験的研究―
1976 年 67 巻 2 号 p. 81-90
詳細
1976 年 67 巻 2 号 p. 81-90
It is the author's opinion that the movable kidney should be divided into the urinary flow-stasis type and the blood flow-stasis type. An experimental study was performed on the blood flow-insufficiency which was supposed to occur in the early period. In the experiment, a dog weighing about 10kg was employed. The kidney was exposed, and under the conditions of various strengths and times of traction, RPF at the time of traction was determined, using indocyanine green as an indicator. Also, under the same conditions, LDH and isozyme were tested, and the influence of the traction against the kidney was pursued. The results obtained are as follows.
1) RPF in the unilateral kidney of the dog was 124.6ml/min on the average.
2) The traction-condition corresponding to the movable kidney is equivalent to 50-100g for 2-4 weeks as the optimal condition, in such a case, RPF was about 60ml/min.
3) In this condition, LDH-total activation was elevated at the highest, while LDH1 was definitely decreased with the changes of LDH-isozyme.
4) From this result, the disorder of the ranal blood-flow due to the renal ptosis seems to affect mainly the renal cortex, and also to activate the factor of capillary vessels and renin's activation.
5) In consideration of the classification of the movable kidney due to LDH-isozyme clinically, mention was made on the analysis of psychosomatic complaints by the change of the fundal arteroles and venules observed in the type of the disordered blood-flow.
