1978 Volume 69 Issue 11 Pages 1512-1521
Leiomyosarcoma of the kidney is a rare neoplasm. Recently we have experienced two cases of leiomyosarcoma of the kidney.
Case 1: A 19-year-old female was admitted because of left flank mass and pain. A left pyelogram showed a shift and displacement of pelvis and calyces. A left renal angiogram showed tumor vessels stain in whole area except the upper pole of the kidney. Under diagnosis of tumor of the left kidney, nephrectomy was performed. The weight of the kidney was 650g. Histological diagnosis was primary leimoyosarcoma of the kidney. After operation the patient was injected actinomycin D 0.4 mg for 5 days. She was quite well without sign of recurrence and metastasis 29 months after operation.
Case 2: A 49-year-old house wife was admitted because of left abdominal mass and pain in April 1977. A left pyelogram and retrograde pyelogram showed a displacement of the pelvis by the tumor. Aortogram showed poor vascularity in the renal mass. The renal mass puncture showed an irregular filling defect. Left nephrectomy was performed after aspiration of about 1000ml bloody fluid. The renal tumor was filled with bloody fluid and necrotic mass. The weight of the kidney was 1630g. Histological diagnosis was primary leiomyosarcoma of the kidney. Chemotherapy with cyclophosphamide, methotorexate, actinomycin D and vincristine was performed after operation. She was quite well 10 months after nephrectomy. We summed up 26 cases of leiomyosarcoma of the kidney including the 2 cases of ours in the literature of Japan, and discussed angiogram and clinical features.