前立腺癌内分泌療法の組織学的治療効果

井坂 茂夫; 赤倉 功一郎; 島崎 淳; 熊本 悦明; 久保 隆; 山中 英寿; 赤座 英之; 阿會 佳郎; 岡田 清己; 馬場 志郎; 片山 喬; 渡辺 泱; 岡田 謙一郎; 園田 孝夫; 古武 敏彦; 宇佐美 道之; 竹中 生昌; 有吉 朝美; 斎藤 泰; 古里 征国; 坂本 穆彦; 矢谷 隆一

doi:10.5980/jpnjurol1989.81.1530

HISTOLOGICAL EFFECTS OF ENDOCRINE THERAPY ON PROSTATIC CANCER

Shigeo Isaka, Koichiro Akakura, Jun Shimazaki, Yoshiaki Kumamoto, Takashi Kubo, Hidetoshi Yamanaka, Hideyuki Akaza, Yoshio Aso, Kiyoki Okada, Shiro Baba, Takashi Katayama, Hiroki Watanabe, Kenichiro Okada, Takao Sonoda, Toshihiko Kotake, Michiyuki Usami, Ikumasa Takenaka, Asami Ariyoshi, Yasushi Saito, Masakuni Furusato, Atsuhiko Sakamoto, Ryuichi Yatani

Author information

Shigeo Isaka
Department of Urology, School of Medicine, Chiba University
Koichiro Akakura
Department of Urology, School of Medicine, Chiba University
Jun Shimazaki
Department of Urology, School of Medicine, Chiba University
Yoshiaki Kumamoto
Department of Urology, Sapporo Medical College
Takashi Kubo
Department of Urology, School of Medicine, Iwate Medical
Hidetoshi Yamanaka
Department of Urology, School of Medicine, Gunma University
Hideyuki Akaza
Department of Urology, Faculty of Medicine, University of Tokyo
Yoshio Aso
Department of Urology, Faculty of Medicine, University of Tokyo
Kiyoki Okada
Department of Urology, School of Medicine, Nihon University
Shiro Baba
Department of Urology, School of Medicine, Keio University
Takashi Katayama
Department of Urology, Faculty of Medicine, Toyama Medical and Pharmaceutical University
Hiroki Watanabe
Department of Urology, Kyoto Prefectural University
Kenichiro Okada
Department of Urology, Fukui Medical School
Takao Sonoda
Department of Urology, School of Medicine, Osaka University
Toshihiko Kotake
Department of Urology, The Center for Adult Disease
Michiyuki Usami
Department of Urology, The Center for Adult Disease
Ikumasa Takenaka
Department of Urology, Kagawa Medical School
Asami Ariyoshi
Department of Urology, School of Medicine, Fukuoka University
Yasushi Saito
Department of Urology, School of Medicine, Nagasaki University
Masakuni Furusato
Department of Pathology, The Jikei University School of Medicine
Atsuhiko Sakamoto
Department of Pathology, Faculty of Medicine, University of Tokyo
Ryuichi Yatani
Department of Pathology, Mie University School of Medicine

Keywords: prostatic cancer, endocrine therapy, histological effects

JOURNAL FREE ACCESS

1990 Volume 81 Issue 10 Pages 1530-1536

DOI https://doi.org/10.5980/jpnjurol1989.81.1530

Details

Abstract

Histological effects of endocrine therapy were evaluated in one hundred and four prostatic cancer patients by new criteria presented by the comittee of “General Rule for Clinical and Pathological Studies on Prostatic Cancer”. Route and time of biopsy, clinical stage and histological grade were related to histological effects. Biopsy specimens taken within three months from the start of the therapy tended to score rather low marks and this tendency is especially apparent with low grade cancers. Histological effects evaluated by the present method correlated well with prognosis in localized stages (stage B, C and D1). In metastatic cases, however, local effects were not related to the prognosis.

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