2000 Volume 91 Issue 9 Pages 637-640
A patient was 31-year-old man with the chief complaint of 38°C fever. He was pointed out left renal tumor by abdominal ultrasonography and computerized tomography (CT). CT revealed left infraclavicular, mediastinal and retroperitoneal lymph nodes swelling and left renal tumor. Serum α-fetoprotein (AFP) and β-human chorionic gonadotropin (HCG-β) level were elevated. The diagnosis of extragonadal germ cell tumor and left renal cell carcinoma was comfirmed pathologically by infraclavicular lymph node and renal biopsy. He was treated with 4 courses of BEP regimen and interferon-α, cimetidine therapy for 2 weeks preoperativelly. After serum tumor markers were normal level, he underwent left radical nephrectomy and left infraclavicular, mediastinal and retroperitoneal lymph node dissection. The histology of all lymph nodes was necrotic tissue, but operation was imcompleted. Therefore VIP therapy was performed postoperativelly. This is the first case of extragonadal germ cell tumor coexsisted with renal cell carcinoma in the world.
