抄録
The purpose of this study was to analyze the factors that influence health-related quality of life (HRQL) in patients with chronic respiratory failure. Subjects were seventeen patients with chronic respiratory failure. HRQL was assessed by means of the St. George's Respiratory Questionnaire (SGRQ) and the scores were compared with physiological measures, 6-minute walking distance (6MWD), activities of daily living (ADL), anxiety and depression. The mean calculated scores of each component (Symptoms, Activity, Impacts and Total) were 69.5, 73.8, 52.6 and 61.8 respectively. The SGRQ scores correlated with degree of dyspnea (the Hugh-Jones scale), vital capacity (VC), VC as percent predicted, forced expiratory volume in one second (FEV1.0), fatigue of the lower limbs, 6MWD, ADL and depression. Four separate stepwise multiple regression analyses were used to identify variables that most influence HRQL. In consequence, body-mass index, ADL, VC, FEV1.0 and 6MWD entered the equations. These findings suggest that, in order to improve HRQL, teaching adequate ADL to reduce dyspnea, training to improve exercise capacity, and to be careful with nutritional and mental status are needed.
