Journal of Physical Therapy Science
Online ISSN : 2187-5626
Print ISSN : 0915-5287
ISSN-L : 0915-5287
Original Article
Antioxidant effect of Phyllanthus amarus after moderate-intensity exercise in sedentary males: a randomized crossover (double-blind) study
Thapanee RoengritPanakaporn WannanonPiyapong PrasertsriYupaporn KanpettaBung-orn SripanidkulchaiJintanaporn WattanathornNaruemon Leelayuwat
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2015 Volume 27 Issue 4 Pages 1181-1186


[Purpose] We aimed to evaluate the effects of Phyllanthus amarus (PA) on oxidative stress and damage, inflammation, and soreness in muscle after a single session of moderate-intensity exercise. [Subjects and Methods] Twelve men randomly participated in 2, three-day phases with a one-week washout period. On the first day, participants consumed two capsules of PA or placebo control (CTL) before 20 min of cycling. They then consumed four capsules on the same day after exercise and six capsules/day for the next two days. Blood samples were obtained before, immediately after exercise and 24 h and 48 h after exercise. The pain tolerance was measured at both legs. [Results] Plasma vitamin C levels in the PA group were higher than those in the CTL group after exercise. At 48 h after exercise, vitamin C levels were higher in the PA group, but those in the CTL group were lower than the pre-exercise levels. However, plasma levels of creatine kinase were increased in both groups after exercise compared with the pre-exercise levels. The neutrophil count was higher immediately after exercise than the pre-exercise levels in the CTL group. [Conclusion] Acute supplementation with PA improves antioxidant status after a single session of moderate-intensity exercise.

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© 2015 by the Society of Physical Therapy Science. Published by IPEC Inc.

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
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