Resistance of silicone rubber membranes to oxygen transfer was measured by use of a specially designed apparatus. In membrane oxygenators the membrane resistance is generally much smaller than the blood phase resistance. Thus, any design which minimizes the blood phase resistance would enhance the gas exchange rate significantly.
Rates of oxygen absorption into saline solutions and blood were measured in a membrane oxygenator in which screens were placed in the blood channels between the membranes for the purpose of reducing the blood phase resistance. The oxygen absorption rate in the new oxygenator is substantially higher than those in the conventional membrane oxygenators. Increases in the rate of hemolysis and formation of emboli in the oxygenator due to the presence of the screens are slight.