Jinko Zoki
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
The genesis of thromboresistance in expanded polytetrafluoroethylene venous prosthesis and the similarity of its surface properties with those of the cardiovascular endothelial lining
H. MATSUMOTOT. KIMURAT. TAKAMATSUE. FUKADAM. SAEGUSA
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JOURNAL FREE ACCESS

1976 Volume 5 Issue 3 Pages 152-159

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Abstract
The results of this experiment definitely indicate that the cardiovascular internal surfaces have a γ C (Zis.) of 29.0 dynes/cm. and γ C (NON-HYDROGHN BONDING) of 68.5 dynes/cm., which is little smaller than a γ H2O of 72.8 dynes/cm. and that γ SL is about zero. Also, the following conclusions are derived that the cardiovascular internal surface is hydrophilic as well as hydrophobic, suggesting that deduction that double configuration of the cardiovascular internal surfaces corresponds to the conformation of cell membrane.
On the other hand, it is indicated that the surface properties of expanded polytetrafluoroethylene can be accompanied by the hysteresis of wettability, thereafter resulting in the almost same surface properties on the portion whose wettability is determined by the nonhydrogen bonding homologous liquids (γ C (Zis.)-γ C (NON-HYDROGEN BONDING)-29.0 dynes/cm., γ SL=0 dynes/cm.).
This experiment also obtained the over all patency rates of 93.3% in the superior vena cava, 86.7% in the inferior vena cava and 81.3% in the portal vein replacement. As mentioned above, the pores in the expanded polytetrafluoroethylene venous prostheses play a major role in antithrombogenicity, including the hysteresis of wettability.
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© The Japanese Society for Artificial Organs
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