As a preparation of human saphenous vein homografts, proteolytis enzymatic digestion using Ficin was mandatory in order to increase the diameter of cadaveric veins.
The appropriate digestion time revealed to be 60-90min. However, the strength of the grafts was reduced in accordance with digestion pretreatment. 1.5% Glutar aldehyde was used for a tanning agent Patients with varicose vein will be good donors because of their increased size of veins Hence we conside to use the saphenous vein from varicose patients as well as from cadavers omitting.
