Abstract
Orally diluting hemofiltration (ODHF), where blood was diluted and supplimented with orally administered electrolytes solution and filtered, was applied to two human uremics after preliminary animal experiments.
The patients well tolerated for longer than 2 months of the observation period and showed no serious complications. Based upon the same principle, a wearable artificial kidney, which was very simple and compact because of no dialysate delivery system needed, was fabricated and clinically used.