1979 年 8 巻 6 号 p. 578-581
The study of analyzing plasma during hemodialysis is one of the most important things for the clinical evaluation of hemodialysis patients, but the extraction of blood samples is not so good for hemodialysis patients.
We thought it then possible to use Ultrafiltrate for analysis instead of plasma, because the concentration of many solutes in plasma related to the concentration of ultrafiltrate, so we developed a new device for continuous sampling of ultrafiltrate.
In using this device in our studies, we have been able to analyze many solutes which are difficult to analyze by the plasma method, for example, organic acids, catechol amines, etc. during hemodialysis continuously.
To analyze ultrafiltrate has many advantages: for example, 1. no necessity for deproteinization, 2. no effect by the enzymes in the blood, 3. easy to micro-analyze in the blood, etc., so this method would be used in clinical evaluation of hemodialysis.