抄録
Many open heart surgery by extracorporeal circulation can be done sefely, especially during operation lasting less than 60 minutes. The advantages of delivering pulsatile rather than nonpulsatile flow during long-time extracorporeal circulation have not been completely established. This study was designed to compare the physiologic and morphological effects of pulsatile and nonpulsatile extracorporeal perfusion on the peripheral vascular circulation for 4 hours in mongrel dogs.
The disporsable pulsatile blood pump for extracorporeal circulation, NIKKISO PP-11, Type has two soft leaflet valves and U-shaped silastic blood chamber.
These experiments suggest that long-time pulsatile pumping extracorporeal circulation offers significant advantages in terms of better physiolosic, morphological effects: higher renal flow, higher renal tissue flow, higher duodenal tissue flow, lower renal vascular resistance, and lesser ultrastructual degeneration of kidney and pancreas.
