抄録
We evaluated a new compound graft made of a non-woven polypropylene sheet enforced by a tetron mesh layer. In canine aortic replacement using our compound graft (6mm in I. D. and 6cm in length), the graft patency rate was 100%, but in canine carotid replacement (4mm in 1.0. and 6cm in length), patency rate was not satisfactory (42.9% of compound graft supported with 4-0 monofillament polypropylene ring were patent, while all of control graft were thrombosed.) In patent cases, we observed the compound graft showed good tissure healings and minimal graft shortening and stiffening after implantation as compared with conventional synthetic vascular prostheses. In conclusion, to provide better antithrombogenicity in early post implantation period, we continue to evaluate this vascular graft with applying modifications to inner surface of our graft.