The effects of recirculating single pass operation of dialysate suply on dialysis performance were investigated experimentally and theoretically for effective use of presentday dialyzers.
First, relationship between KA and QD for some commercial dialyzers were examined in vitro for determination of solute removal behavior due to dialysate recirculation.
Next, the amount of recirculating dialysate is responsible for the decrease of drivingforce between blood and dialysate concentration. this fact can be explained theoretically with our 3pool model presented earlier.
Third, relatively large molecule substances are removed more efficiently in RSP than in SP. The in vivo results in Recirculating Single Pass Operation using hollow fiber dialyzers were found to be well explained with our 3pool model.
The chemical engineering techniques are effective enough for understanding the clinical conditions of a renal failure patient.
