An Approach to Symptomeless Hemodialysis by a Progrmmed Control of Blood Flow Rate (PRODIS)

抄録

An approach intended to prevent HD-induced symptoms is described. This method called ‘PRODIS’ (Programmed Dialysis) is characterized by enhancing the dialysis effeciency gradually during dialysis in order to avoid osmotic imbalance over the body fluid. A one-pool model of the patient-hemodialyzer model is used to ensure the same total removal amount as compared with conventional dialysis. The application of an automated device has prevented the disequlibrium syndrome such as headache and hypotention remarkably. A parameter representing ultra-filtration-compensating ratio (UFCR) was introduced to show that an increase in the UFCR due to PRODIS is effective in preventing hypotention.