Abstract
Changes in the levels of γ-glutamyltranspeptidase (GGT) and alkaline phosphatase (AP) were measured in control subjects and in patients with renal and non-renal diseases. The ion retardation chromatographic method was employed for estimating the GGT activity. Both GGT and AP levels were increased in renal disorders associated with nephrotic syndrome. In acute nephritis there was a slight increase or normal levels in both enzyme activities. In renal failure of different etiologies the GGT levels were either normal or decreased whereas in 34% cases the AP activity was increased, Among non-renal diseases, in leukemia there was a significant increase in the levels of GGT in all cases investigated. On the other hand only in about half of the cases, the AP level was found to be increased.
