2019 Volume 23 Issue 1 Pages 37-42
Objective: This study aimed to evaluate associated factors with postoperative infectious disease in patients undergoing elective open heart surgery, in particular focusing on nutritional conditions and tissue perfusion.
Method: Individuals who were scheduled to undergo open heart surgery in a tertiary-care hospital in Japan between April 2014 and December 2016 were eligible for enrolment in the study. Postoperative infectious disease included catheter infection, wound infection, and pneumonia. A controlling nutritional (CONUT) status score was used as an index of nutritional status, and a difference in CO2 partial pressure of arteriovenous blood (CO2 difference) was used as a tissue perfusion index.
Multiple logistic regression analysis was conducted to determine independent factors associated with postoperative infectious disease.
Results: Ninety-two patients of 157 patients were malnourished and mean CO2 difference was 3.9 mmHg. Twenty-one patients had postoperative infectious disease. Body mass index, duration of surgery, postoperative lactate level, diabetes, glomerular filtration amount, and duration of postoperative artificial respiration were associated with postoperative infectious disease.
Conclusion: Preoperative nutritional status and tissue perfusion index were not significant factors of infectious disease after open heart surgery.