Establishment of Steroid Glaucoma Rabbit Strain

Abstract

Steroid glaucoma is difined as increase of intraocular pressure (IOP) instillation of steroidal drug. Ii is suggestied that this disease could begenetic. We attempted to establish the steroid glaucoma breeding among pigmented rabbits increased the IOP by instillation of steroid. Steroid was instilled to 65 rabbits twice daily. After 2 weeks, teenty five rabbit showed the increase of IOP. After 3 month, We tried to instille steroid to rabbits wishid incvesed IOP, But none of them showed the increse of IOP. These risults suggest that growth during the three month might caused elimination of response and consideration should be given to the setting of the study period.