2025 Volume 44 Pages 65-71
Retinal prosthesis is a medical device designed to restore vision in patients who have lost sight due to photoreceptor degenerative disorders, such as retinitis pigmentosa, by electrically stimulating the remaining retinal neurons. Three major approaches—epiretinal, subretinal, and suprachoroidal implantation—have been developed, each with unique technical advantages and limitations. Clinical studies of devices such as the ARGUS II, Alpha IMS/AMS, PRIMA, and suprachoroidal-transretinal stimulation have demonstrated partial recovery of visual functions and modest improvements in daily activities. However, the level of vision achieved remains significantly below that of natural sight. This review summarizes recent advances in retinal prosthesis research, highlights clinical study outcomes, and discusses future prospects.
