Abstract
We have experienced blood line coagulation in blood delivery equipment five out of the 39 times we have used hemodialysis with FUT anticoagulation.
We therefore studied whether there were any clinical differences between patients who suffered blood line coagulation with FUT anticoagulation and those who did not. All patients studied were under hemodialysis treatment with FUT anticoagulation. With regard to the dialyzer membrane, the frequency of blood line coagulation was high with hemodialysis using a PAN (polyacrylonytrile) membrane. Clinical data showed that changes in hematocrit (Hct) during the two weeks before FUT dialysis were significantly higher in patients who suffered blood line coagulation than in patients who did not (p<0.05). There were no differences between the two groups in blood platelet counts, white blood cell counts. serum Ca concentrations or blood flow volumes.
These results suggest that in hemodialysis with FUT anticoagulation, the dosage of FUT must be increased in patients with a recent abrupt increase in Hct. In addition, an appropriate dialyzer membrane must be used to prevent blood line coagulation.
