Abstract
Antimicrobial use and antimicrobial resistance rates were studied at 7 medical facilities, which belonged to the Northern Nagano medical district, during a 5-year period from January 2007 to December 2011. The results showed that cefotaxime+ceftriaxone- or levofloxacin-resistant rates in Escherichia coli were significantly increasing not only in each facility but also in the whole network (Infection Control Network of Northern Nagano), and antimicrobial use was tending to increase within the whole network. According to the results, we considered that antimicrobial use and resistance rates in E. coli required surveillance in the whole region as well as in each facility. On the other hand, the carbapenem-resistant rate in Pseudomonas aeruginosa was hardly changing both in each facility and the whole network, and carbapenem use was also unchanged in the whole network. Therefore, antimicrobial use and resistance (AUR) surveillance for P. aeruginosa should be maintained in each facility, and confirming the AUR surveillance level of individual facilities in the region should be useful.
