Japanese Journal of Infection Prevention and Control
Online ISSN : 1883-2407
Print ISSN : 1882-532X
ISSN-L : 1882-532X
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Antimicrobial Stewardship Pharmacist-driven Prospective Audit and Feedback of All Intravenous Antibiotics in a Middle-sized Community Hospital
Yasuhiro SASAKIAkira KURISHIMAMisato AMANOAyumi KANAMARUAkiko YAMAKUCHIHirobumi TAKAYASUYoshiro HADANOMasataka YANO
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2021 Volume 36 Issue 2 Pages 117-122

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Abstract

The guidelines recommended formulary restriction and pre-authorization and prospective audit and feedback. In Japan, there are some reports of intervention and feedback for all injectable antibiotics from large hospitals, but none from middle-sized hospitals. This study aimed to assess the impact of prospective audit and feedback for all injectable antibiotics of antimicrobial stewardship (AS) pharmacists in changes of antibiotic agents in middle-sized hospitals. The days of therapy per 1,000 patient-days (DOT/1000pd) of all injectable antibiotics significantly decreased from 248.6 to 217.1 (12.7%) after intervention. Furthermore, DOT/1000pd of anti-pseudomonas agents significantly decreased from 60.0 to 35.5 (40.8%). All antibiotic costs were reduced by about 50,000 yen (18.4%) monthly. A hospital policy to optimize antimicrobial prescription introduced by AS pharmacists decreased antibiotic consumption, especially wide-spectrum agents.

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© 2021 Japanese Society for Infection Prevention and Control
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