1991 年 50 巻 Suppl-7 号 p. 118-121
Ten minutes after an intravenous injection of HRP, guinea pigs were killed by decapitation. The bullas were removed and opened, and the cochleas were fixed by perilymphatic infusion with glutaraldehyde. Blood shudging and considerable HRP leagage were observed in the capillaries of the stria vascularis. When blood was replaced with plasma expander, blood sludging did not appear after decapitation because few blood cells remained in the capillaries. Moreover, HRP leakage was scarecely observed in the strial capillaries. Even if the strial capillaries were contracted by the decapitation, HRP leakage did not occur without blood sludging. The high pressure between capillary endothelium and blood cells produces many marginal bolds, which efficiently transport HRP out of the capillaries.