自律神経失調と起立性調節障害を伴うめまい症例についての臨床的検討

抄録

Equilibrium function, psychological tests, and a questionnaire about orthostatic dysregulation were investigated in 103 patients who visited the laboratory of equilibrium function in Kumamoto University hospital from April 2004 to December 2005. The percentage of patients with autonomic nerve dysfunction comprised 42.7% of the total patients. Most (94%) of the patients with autonomic nerve dysfunction presented with orthostatic dysregulation. The patients with autonomic nerve dysfunction and orthostatic dysregulation showed several diagnoses by the equilibrium function test: peripheral vestibular disorders (37%), disease of the central nervous system (28.6%), abnormal blood pressure (75%), psychogenic disorders (100%), and origin unknown (14.3%). Tofisopam was effective in 60% of the patients with autonomic nerve dysfunction and orthostatic dysregulation. In the other patients, only 18.5% were naturally cured without medication. There was a significant difference between the group of patients treated with Tofisopam and a control group without medication. Tofisopam tended to be effective in patients whose blood pressure decreased by the schellong test. We consider that it may be possible to improve the curative effect on vertiginous patients by performing psychological tests and questionnaires about orthostatic dysregulation, adding to the routine equilibrium function tests including the schellong test.