Chemotherapeutical Studies on Furazolidone against Edwardsiellosis in Cultured Eel
1980 Volume 15 Issue 1 Pages 31-36
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1980 Volume 15 Issue 1 Pages 31-36
Antibacterial activity of furazolidone (N-(5-nitro-2-furyliden)-3-amino-2-oxazolidone, FZD) against Edwardsiella tarda isolated from diseased eel, Anguilla japonica, and therapeutic effect of the drug by medical bath against experimental Edwardsiellosis in young eel were studied.
Minimal inhibitory concentration of FZD against 30 strains of E.tarda was 0.03-5.0ppm and sensitivity distribution curve had two peaks. One peak was at 0.07 ppm and the other at 1.2 ppm.
FZD was highly effective by medical bath at over 1ppm against experimental Edwadsiellosis with E. tarda A strain (MIC was 0.07 ppm) and effective at over 4 ppm with E. tarda B strain (MIC was 1.2 ppm).
