Abstract
The cancer screening guidelines that have evaluated the efficacy in terms of mortality reduction are important. In addition, it is important to apply results obtained in fundamental experiments and clinical studies to cancer screening. Many results suggest that H. pylori infection should be considered a prerequisite for the occurrence of gastric cancer, and that mucosal atrophy of the stomach markedly correlates with the occurrence of gastric cancer. According to the ABC classification, it is possible to categorize the risk for gastric cancer by a combination of simple blood tests for the H. pylori antibody and pepsinogen method. The ABC classification is very likely to contribute positively to gastric cancer screening in appropriate combination with imaging modalities. However, it must be conducted carefully step by step with scientific inspections.
