2017 年 27 巻 1 号 p. 3-12
The deep-sea in our planet is characterized as the extreme world placed under high-hydrostatic pressure. We have identified many of living creatures in the deep-sea environment, and several high-pressure loving organisms, called “piezophiles”, have been found and isolated using the manned and unmanned deep-sea submersible systems. Then, this extreme world is being more and more elucidated. In this article, the fascination to investigate the mysterious world, deep-sea, is introduced, then, the strategies for adaptation to the high-pressure condition in microorganisms are illustrated at the molecular levels. Finally, the next stage to study the pressure life science would be discussed.