好中球のスーパーオキシドアニオン (O^-₂) 産生能に及ぼすプライミング効果

抄録

Under opsonized zymosan (OZ) stimulation, the cypridinaluciferin analog dependent chemiluminescence (MCLA-CL) of neutrophils (PMNs) shows a different luminescence pattern with and without infection. The noninfected PMN shows the same luminescence pattern as with infection, when primed by tumor necrosis factor (TNF), f-methi-onyl-leucyl-phenylalanine (FMLP) and phorbol myristate acetate (PMA) . From these findings, it is considered that the PMNs when infected, is primed by an increasing number of various mediators.