Synovial Sarcoma of the Hand in a Patient with Rheumatoid Arthritis Treated Successfully with Chemoradiotherapy and Finger Ray Amputation

Abstract

A 55-year-old woman with rheumatoid arthritis (RA) presented with a lump of the right palm. The tumor was diagnosed as a synovial sarcoma by an incisional biopsy. After chemotherapy and radiotherapy, ray amputation of the index finger was performed and was followed by postoperative chemotherapy. At 47 months postoperatively, the patient had no evidence of tumor recurrence. When clinicians see a growing nodular lesion that does not respond to antirheumatic therapy in an RA patient, they should perform radiological and histological examinations to differentiate neoplasm from inflammatory lesion.