2018 Volume 38 Issue 4 Pages 478-483
In the veterinary field, canine otitis is one most common infectious disease. However, it occur a problem that inproper usage of antibiotics induces resistant bacteria. In the present paper, as a novel therapy against infectious otitis, we describe fundamental studies of photodynamic antimicrobial chemotherapy (antibiotic PDT) and its clinical application using existing dye and novel chlorine derivative photosensitizer.