Abstract
To investigate effects of the combination of ultrasonic irradiation on the photodynamic therapy (PDT). PDT combined with ultrasonics was performed on the erythrocyte and the cytocidal effect was evaluated from the hemolytic quantity using the absorption wave length at 414nm. In this study, the three type of PDT were carried out and compared. One was a PDT with HpD by Ar-Laser irradiation, and others were with Pc by He-Cd or Kr Laser irradiation. Some ultrasonic power (1MHz, 0.2W/cm2) was irradiated to the all types of PDT at the same time as the laser irradiation. The results indicated that cytocidal of PDT combined with ultrasonic was better than that on an ordinary PDT in this study.