抄録
Photodynamic therapy (PDT), in which hematoporphyrin derivative is activated by an argon-dye laser, was performed on superficial bladder tumors and CIS. The effectiveness of spot PDT using a 400μm quartz fiber and cystoscope in 51 superficial tumors is limited to tumors ≤ 2cm in size and in such cases the light intensity should be 300mW/cm2 for ≥ 5 to 10 minutes. For the CIS therapy in 18 cases, whole bladder wall PDT using a motor driven laser light scattering optic was used. The total light dose of 30J/cm2 or more may be useful for the CIS. Problems and counter-measures PDT are discussed and gold vapor laser is recommended to increase PDT effect.
