昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Cambarus clarkiiのE. C. G.に及ぼす薬品ならびにイオンの影響
鳥海 博海野 一菊池 毅須田 登
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ジャーナル フリー

1956 年 16 巻 2 号 p. 89-96

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The authors induced the action current of the heart in situ of Cambayus claykii through cotton thread elctrode, and recorded it with a cathode ray oscillograph for observation.
In the present work, the authors were successful in a simultaneous recording of the spike potential (neurogenic action current) and the slow potential (myogenic action current) from the heart of Cambayus claykii.
Acethylcholine increased the amplitude and frequency in the E. C. G. of Cambayus claykii.
Adrenalin diminished the amplitude in the potential fluctuation.
Atropine diminished the action potential, and interrupted the heart beat when applied for a long period of time.
Eserine increased the slow potential and increased the repetitive response.
Pilocarpine increased the number of slow potentials and simultaneously increased the number of neurogenic spike discharges.
Prostigmine increased the spike (neurogenic) potential and slow (myogenic) potential, and increased their frequency.
TEA transitorily increased the slow potential.
Curare indicated no noteworthy influence on the ECG of Cambayus claykii.
Mg _??_interrupted the heart beat, and later, it gave rise intermittently a storm of slow potential and the spike potential.
Ca _??_and K _??_ lowered the excitability of the heart muscles.
LiCl gave rise a phenomenon similar to the fibrilation observed in the heart of vertebrates.
In view of the above, the authors came to the conclusion that the neurodendrites from the ganglion, which is the pace maker in the heart of Cambayus claykii, belong to the cholinergic nerve.
In short, the authors concluded that the neurodendrites from the pace making ganglion of the heart of Cambayus claykii possesses the property similar to that of the parasympathetic nerve of vertebrates, and that it is connected to the muscle fibres through end apparatus which can be blocked with Mg _??_, thus the neurodendrites may belong to the cholinergic nerve.

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