Abstract
A rapid progress was recently made in the studies on the end-plate potential. The morphological structure of the end-plate and the impulse transmission mechanism at the end-plate have been generally made clear.
The authors have firmly established the method to lead the end-plate potential in a simple manner by the separate lead method. In the present paper, the precedures are described and a few results obtained thereby are reported.
By means of the separate lead method, the end-plate potential cliff ereuce at a given locality can be lead in simple manner employing curarized muscle and normal muscle. For curarization, injection of 4 cc of 3 mg/cc solution of d-tubocuraline into the arterial arc of Bufo vulgaris. Further, the combined use of KCl, the end-plate potential of single side can be lead. By this method, the distribution of the end-plates of the M. sartorius of Bufo vulgaris can be learned.
This new method of recording the end-plate potential is considered to be applicable to a broad extent due to its simplicity.
