The activities of liver enzymes in mice were studied in various stages of the infection with Scllistosoma japonicum.
The activities of catalase, arginase, cholinesterase, and esterase showed a progressive decrease in the late stage of the infection in Schistosomiasis.
Alkaline phosphatase activity showed a slight increase in that stage. However, all enzymes in liver of mice tested showed reduction of activities in the early stage of the infection.
The decrease of activity of catalase was proportional to the number of cercariae infected in some extents. A toxic influence of cercariae of S. japonicum to mice is suggested.