Sodium glucuronate isonicotinyl hydrazone (INHG) 並びにIsonicotinic acid hydrazide (INAH) の鷄胎仔に及ぼす影響に就いて

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On comparison of the mortality of chick embryos between INHG and INAH, the toxicity of INHG was found to be lower than that of INAH and the growth inhibition due to the administration of INAH was found to be moderated by its administration in the form of INHG. On quantitative determination of INAH contained in the allantoic fluid, in either case of the administration of INAH or INHG, the amount of excretion was found to increase following the increase in the dose administered and the maximum excretion during the course of incubation was observed in the middle stage. Increase in the hepatic weight was better among the embryos administered of INHG than those received INAH but the amount of INAH contained in the liver was larger among the embryos administered of INAH than those received INHG.