1967 年 27 巻 11 号 p. 862-866
Twenty cases with the combined symptomes of hypertension, diabetes mellitus and arteriosclerosis were studied by means of fluorescein f undus photography using 10ml of 10 % fluorescein sodium solution.
No side effects were observed either on pulse or on blood pressure, however xanthopsia occured in 9 cases and yellowish coloration of the skin developed in 18 cases, the incidence of either of them being higher than those used 5 ml of 5 % fluorescein sodium solution.
The frequency of nausea or vomitting among side effects might be similar to or even less than that with the 5 % solution, if careful consideration was taken to the personal general health before the administation.
Moreover, the time, during which fluorescent pattern produced with 10 % solution permitted to be photographed, was twice as much as that with the 5 % solution. The contrast between the fluorescent pattern and the background on the photograph was more distinct than that of the 5 % solution.