It is the present situation that there is no suitable substance which is very effectively accumulated in tumor (tumor affinity agent) . 67Ga-citrate is, however, relatively accumulated in tumor tissues, and it has been extensively used clinically
Our present report dealt with the investigation of scintigraphy with 67Ga-citrate, for several kinds of malignant and benign tumors. Scintigrams of 116 patients with tumor were observed at 48 hours after 67Ga-citrate 1.5-2.0 mCi injection.
Eighty-two percent of lung cancers, 71 percent of malignant lymphomas and 59 percent of laryngeal carcinomas showed positive findings.
As localization of the tumors are concerned, most of them in the head and neck and the chest showed positive findings. However, owing probably to accumulation of the nuclide in intestine and bone, negative findings were frequently the results in malignant lymphoma in abdomen.
67Ga-citrate-scintigraphy should be useful for detecting tumor in the head and neck and the chest, and for determining clinical stage of malignant lymphoma. And it could be contributable to radiation therapy or surgical operation and following up of the disease in size and extent. Whol body scintigraphy could find metastases with no physical findings.
