At present, to estimation of antistreptolysin-O (ASO) titer, Rantz-Randall's method has been usually used in routine laboratory. The Rantz-Randall's method, however, is cumbersome, time-consuming and requires more skillful technics, too.
Recently, a new method for estimation of ASO titer with streptolysin-O combined polystyrene-latex reagent had been developed by Behringwerke and we have investigated it.
In our examination, we have compared with the titers between Rantz-Randalls' and new method and examined the relationship between the results of CRP, RA, and betalipoprotein index and the results of this new method.
Our conclusions were as follows:
Samples which obtained above 250 or under 166 Todd units showed 96.6% and 31.4% positive, respectively, by this method. No relationship between the results of CRP, RA, and beta-lipoprotein and this method was observed. And so, it is found that this new method is very suitable screening test for ASO by the reason of it's simplicity and rapidity.