1977 年 37 巻 3 号 p. 293-300
The leukemic reticulosis is a disease with acute process and its unknown reality. The two cases described in this paper.
Case 1. A 64 year old woman. On admission, the white blood cell count was 84, 800/cmm with 77 per cent reticulum cells. She presented with swelling of lymph nodes and enlargement of spleen, both of which revealed proliferation of reticulum cells. The frequency of tumor cells was as low as 1.2 per cent in bone marrow. This case could possibly be identified as reticulosis originated from lymph nodes or spleen.
Case 2. A 20 year old woman. On admission, the white blood cell count was 1, 500/ cmm with 86 per cent reticulum cells. Proliferation of reticulum cells were noted in bone marrow and spleen, but no remarkable proliferation were noted in lymph nodes. This case was suspected that these abnormal cells were originated from spleen on autopsy findings.
In both cases, these cells were positive for acid phosphatase reaction, and its morphological and cytochemical findings also indicated characteristics of leukemic reticulosis.