Abstract
46 cases of pm cancer (gastric cancer with invasion into the proper muscle layer) diagnosed by macroscopic appearance, at our hospital between 1975 and 1983 were examined clinicopathologically. The results were: 1. pm cancer in 13.9 % of all cases of resection. Macroscopically, the Borrmann type comprised 69.6 % of pm cancer, more frequent than the early advanced type (30.4 %) . The mean age was 54.8 years. pm cancer affected males most often. 2. Most pm cancer was located in the A area. There was no difference in location of the early advanced type and the Borrmann type. The Borrmann type 1 cancer, however, was often located in the C area. 3. The pm cancer was usually larger than 2.0 cm in diameter. The rate of lymph node metastases was 41.3 %, and there was no difference among the macroscopic types. On the Borrmann type cancer cases, 6.5 % were n2 positive. 4. Lymphatic invasion was often observed in pm gastric cancer (84.8 %), and severe lymphatic invasion to ly2 or ly3 was seen, particularly in the Borrmann type. Venous invasion was observed in 17.4 % of the Borrmann type cancer. 5. Histologically, the differentiated type accounted for most of the pm gastric cancer, both Borrmann type 1 and Borrmann type 2. Borrmann type 3 cancer accounted for most of the undifferentiated type. There were no differences between the differentiated and the undifferentiated types in lymph node metastasis.