2016 年 54Annual 巻 27AM-Abstract 号 p. S156
Oxygen plasma has been known as enhanced hydrophilic treatment techniques for surface modification.In this study, we investigated effect of oxygen plasma on characterize changes of PLLA fiber sheet and cell adhesion. The PLLA fiber sheet was fabricated by using CO2 gas laser supersonic drawing and the oxygen plasma treatment was performed by r.f. plasma CVD technique. After the plasma treatment, characterized changes of the surface was analyzed by X-ray photoelectron spectroscopy (XPS). The C=O bond ratio of the PLLA fiber sheet surface was increased. Additionally, NIH3T3 cells were spread on the plasma treated PLLA fiber sheet. The cell behavior was analyzed for 50 hours. In an early stage of cell culture, the cell adhesion and proliferation was accelerated by increased C=O bond of the PLLA fiber sheet. It was observed that the oxygen plasma treatment increased C=O bound and had enhancement of cell proliferation.