Magnetic resonance imaging (MRI) is one of the most promising non-invasive methods to evaluate the organ functions. Especially, arterial spin labeling (ASL) method provides the information of the blood perfusion status without using contrast media. And diffusion weighted image (DWI) method, which can detect the diffusion of the water of tissue and organ, has a potential to reflect the perfusion status, too. However, we cannot distinguish perfusion from diffusion exactly by boxel size in vivo. Then, we tried MRI analysis by ASL and DWI, using the extracorporeal perfusion model of the pig kidney isolated after slaughtering. An electrolyte solution was perfused at the pressure of 30mmHg from the artery by drip infusion, and the perfusion study was carried out by ASL and DWI. As a result, although neither typical perfusion nor infarction clues were detected by ASL, a slight clue of perfusion could be detected by DWI.
