Surgery is an effective treatment for intractable temporal lobe epilepsy where the seizure cannot be controlled by medication. Intractable epilepsy is treated by removing epileptic foci and propagation paths. In surgery, it is important to determine epileptic foci and propagation paths. In this report, we propose a new method to visualize the connectivity among the channels of electrocorticogram(ECoG). The connectivity strength is defined as linear combination of the maximum correlation value and its delay time between channels of ECoG. Then, we estimated the propagation structure of patients with intractable epilepsy using minimum spanning tree whose edge length was connectivity strength. We estimated propagation structure of epileptiform discharges from two ECoG who patients of intractable temporal lobe epilepsy using the connectivity analysis. The results show the same medical opinion obtained by PET analysis. Therefore the proposed method is considered an effective analysis method as a diagnostic indicator of objective evidence.
