Visualization of Thrombus Formation on Shear Flow and Numerical Simulation for the formation by Transport Equation

Abstract

This paper describes the visualization of thrombus formation on shear flows such as orifice flow and Cuette flow, and development of numerical simulation for predicting thrombus formation by transport equation. Using the transparent devices, the thrombus formation on the wall on shear flow is observed and obtained the rate of thrombus formation by image processing. The results showed that the thrombus rate is increasing with shear rate by changing geometries of orifice and rotational speed of Cuette flow. On the other hand, the prediction method using CFD including transport equation of species using modified shear dependent model in orifice flow and Cuette flow is developed. In this computation, activated platelet is evaluated. The results show that deposition rate of activated platelet is increasing with shear rate.