2017 Volume 55Annual Issue 5PM-Abstract Pages 482
In this study, a combination treatment system of cryosurgery and hyperthermia treatment was fabricated and evaluated. This system consists of a surgical probe and a coolant circulation system. In the system fabrication, Peltier device with a surgical probe tip was adhered to a metal circular disk attached to a plastic pipe. A coolant chamber was bonded to Stirling cooler. And the flexible tubes for the coolant circulation were attached to the chamber. The probe and the chamber was connected with the tube, thus the treatment system was fabricated. In the evaluation test of the system performances, the temperature of the probe reached to -46.6 degrees C. Temperature cycles of the freezing and the warming automatically was repeated at three times in the temperature cyclic test. In the animal test, the necrosis was observed in the tissue after the combination treatment. These results suggest the effectiveness of the combination treatment.