Abstract
In this study, a new device utilizing micro three-dimensional vibration stage is developed to control cell culture. This device is able to enforce three-dimensional dynamic stimulations to the cell. Experimental studies have been carried out by using normal human osteoblast. Developed vibration stage, in which doubly L-shaped clamped-free beam type vibrator is utilized, has quite simple structure and is able to sterilize itself easily. The studies have shown that the cell has capability to detect dynamic stimulations and to change its own figure.