Abstract
When we develop artificial organs, which contact with blood, hemocompatibility of materials should be considered. However, assessing hemocompatibility of materials is difficult, because platelet adhesion, an indicator of hemocompatibility, occurs through lots of factors. Especially, although the effect of shear stress is thought to be most important factor, reports thus far have ignored it. Therefore we developed a system to evaluate test materials by using human blood, under shear flow conditions. Our system could visualize human platelets flowing, rolling, and adhering to opaque materials in real time under shear stress. The number of platelets adhering to "HUVEC on glass" is less than any other materials under a shear stress of 0.05Pa.
